Regis is a frequent guest to NTS, appearing on various shows between 17 June 2018 and most recently on 12 November 2025. Regis has been played over 170 times on NTS, first on 16 October 2012. Regis's music has been featured on 162 episodes.

Regis is one alias of Karl O'Connor, a Birmingham techno producer and founder of the Downwards imprint; other projects include Kalon, British Murder Boys alongside label-mate Anthony Child (Surgeon) and involvement with the enigmatic Sandwell District imprint.