Destiny's Child has been played on NTS over 160 times, featured on 163 episodes and was first played on 19 November 2013.

Destiny's Child was an American girl group whose final and best-known line-up comprised Beyoncé Knowles, Kelly Rowland and Michelle Williams. The group began their musical career as Girl's Tyme, formed in 1990 in Houston, Texas. After years of limited success, the quartet comprising Knowles, Rowland, LaTavia Roberson and LeToya Luckett were signed in 1997 to Columbia Records as Destiny's Child. The group was launched into mainstream recognition following the release of the song "No, No, No" and their best-selling second album, The Writing's on the Wall (1999), which contained the number-one singles "Bills, Bills, Bills" and "Say My Name". Despite critical and commercial success, the group was plagued by internal conflict and legal turmoil, as Roberson and Luckett attempted to split from the group's manager Mathew Knowles, citing favoritism of Knowles and Rowland.

In early 2000, both Roberson and Luckett were replaced with Williams and Farrah Franklin; however, Franklin quit after five months, leaving the group as a trio. Their third album, Survivor (2001), whose themes the public interpreted as a channel to the group's experience, produced the worldwide hits "Independent Women", "Survivor" and "Bootylicious. In 2001, they announced a hiatus to pursue solo careers. The trio reunited three years later for the release of their fifth and final studio album, Destiny Fulfilled (2004), which spawned the international hits "Lose My Breath" and "Soldier (feat. T.I. & Lil' Wayne)". Since the group's official disbandment in 2006, Knowles, Rowland and Williams have reunited several times, including at the 2013 Super Bowl halftime show and 2018 Coachella festival.

Destiny's Child has sold more than sixty million records worldwide to date. Billboard ranks the group as one of the greatest musical trios of all time, the ninth most successful artist/band of the 2000s, placed the group 68th in its All-Time Hot 100 Artists list in 2008 and in December 2016, the magazine ranked them as the 90th most successful dance club artist of all time. The group was nominated for 14 Grammy Awards, winning twice for Best R&B Performance by a Duo or Group with Vocals and once for Best R&B Song.